The Neverfull was introduced in 2007, and Sotheby's calls it one of Louis Vuitton's most successful handbag designs since the Keepall and Speedy. It is a roomy open tote with laces at the sides that let the owner pull in or loosen its shape, and it comes in three sizes, PM, MM and GM. Sotheby's says the largest can carry up to 200 pounds, about 90 kilograms.

In 2014 Louis Vuitton updated the design with a removable matching pochette that can be used separately as a clutch or wristlet. The classic versions are in Monogram, Damier Ebène and Damier Azur coated canvas, and it is also made in Epi leather. Each year Louis Vuitton issues limited editions that are sold for one season only.

The Neverfull has been used for artist editions too, including a Monogram Multicolore version printed with Takashi Murakami's MOCA Hands from 2007.