Fabio d'Angelantonio was born in Rome in 1969. He graduated in economics from LUISS University in Rome and took an MBA in international management at the United Business Institutes in Brussels. His first jobs were in Spain and Belgium, in marketing at Olivetti and then at the European Commission; at 23, working for a textile company, he had his first meeting at Loro Piana's headquarters.
From 1995 to 2000 he was international sales and marketing director of Editions Hemma, a Belgian children's book publisher. In 2000 he moved to Milan as a product manager at Ciaoweb, the internet portal of the Fiat group, and in 2001 joined Merloni Elettrodomestici, later Indesit, as brand and advertising manager. In 2005 he became chief marketing officer of Luxottica, in charge of marketing and communication for its brands and licences, especially Ray-Ban, Persol and Oakley, and from early 2009 he was also president of its Sunglass Hut chain of about 3,500 stores in 30 countries. He has lectured at SDA Bocconi and on Bocconi's fashion management master's.
In September 2016 LVMH appointed him chief executive of Loro Piana, succeeding Matthieu Brisset; the Corriere della Sera noted that the company was once again led by an Italian. A customer of the brand for some 25 years, he said his goal was simple: "to sell the most beautiful cashmere sweater in the world." He developed a careful retail strategy in Asia, prepared entry into the Middle East and grew categories such as shoes, and in 2021 commissioned the brand's first capsule collaboration, with Hiroshi Fujiwara of Fragment. He left on 15 November 2021 after five years, handing over to Damien Bertrand; Antoine Arnault thanked him for steering Loro Piana's transformation from a family business into an LVMH house.
Casadi has not verified his role since leaving Loro Piana in 2021.