Dario Vitale was born in 1983 near Naples and graduated from the Istituto Marangoni in 2006. He began his career at Dsquared2 and then worked at Bottega Veneta under Tomas Maier.
In 2010 he joined Miu Miu, where he spent some fifteen years and rose to ready-to-wear design director and head of image, working closely with Miuccia Prada until he left in January 2025.
On 1 April 2025 Versace appointed him chief creative officer, the first person from outside the Versace family to lead the house after Donatella Versace stepped down in March. His first and only collection, Spring/Summer 2026, was shown on 26 September 2025 at the Pinacoteca Ambrosiana in Milan, on deliberately untidy domestic sets. It reread the house's 1980s codes for everyday dressing: vivid colour, high-waisted jeans, cut-out muscle T-shirts, undone belts and zips, backless dresses and power shoulders. Reviewers were divided but engaged, and Vanessa Friedman of The New York Times called it one of the most buzzed-about, debated and potentially influential collections of the season.
On 12 December 2025, after the Prada Group completed its acquisition of Versace, he was dismissed. In September 2026 he was appointed creative director of Emporio Armani and of accessories at Giorgio Armani.
Casadi has not confirmed the details of his Giorgio Armani brief beyond the September 2026 announcement as reported on Wikipedia.